Research inventory

BOON Thierry

UCL 74.59, AVENUE HIPPOCRATE, 74
1200 BRUXELLES
BELGIQUE

Phone : +32 2 764.74.59
Fax : +32 2 764.94.05
E-mail : Thierry.Boon@bru.licr.org

The GECE Unit specializes in cancer immunology and cancer genetics. The notion that the immune system might be enlisted to rid the body of cancer draws on past work at the Unit which revealed that most human tumors bear antigens that can be recognized by cytotoxic T lymphocytes (CTLs). Some of these antigens are highly tumor-specific, others are expressed on certain normal cells. A number of antigens have been found on many different types of tumors, suggesting that a therapeutic strategy targeting such antigens could be used to treat a wide range of cancers. The GECE Unit continues the search for tumor antigens, and evaluates their therapeutic potential in vaccine trials of cancer patients. More recently, the Unit has started to study the mechanisms of inhibition of the T cells in tumors.

Cancer, Immunology, Immunotherapy

Recherches cliniques en immunothérapie du cancer avec de nombreux centres européens, dont:
Université catholique de Louvain - Cliniques universitaires Saint-Luc
Institut Bordet, Brussels
Hopital Erasme, Brussels
Hotel Dieu, Nantes
Institut Curie, Paris

Patent(s) : yes
Licences : yes

Number of researchers : 47 - Number of technical and administrative staff : 46

- Prix Rik et Nel Wouters pour la recherche sur le cancer, 1986.
- Prix De Vooght d'Immunologie, 1986.
- Dr Joseph Steiner Cancer prize, 1990.
- Prix Francqui, 1990.
- Prix Louis Jeantet, 1994.
- Rabbi Shai Shacknai Memorial Prize in Immunology and Cancer Research, 1994.
- Prix Sandoz d'Immunologie, 1995.
- Prix Léopold Griffuel, 1999.

Training : no