Research inventoryLaboratory of physiological Chemistry
(Faculté de médecine / Département de biochimie et de biologie cellulaire / BCHM)
Person(s) in charge of the research unit
VAN SCHAFTINGEN Emile, président d'unité, OPPERDOES Fred, VIKKULA Miikka
Address
Scope of the research unit
The research of the Biochemistry Unit can be divided into seven subjects :
• studies on carbohydrate metabolism: deglycation of proteins (E. Van Schaftingen, M. Veiga-da-Cunha;http://www.icp.be/grm)
• characterisation of hereditary neurometabolic diseases (E. Van Schaftingen, M. Veiga-da-Cunha;http://www.icp.be/grm)
• metabolism of nucleoside analogues used in anticancerous therapy (F. Bontemps, E. Van Den Neste; http://www.icp.be/grm)
• genetic studies on (lymph)vascular anomalies, cardiopathies, cleft lip and palate, and cancer (M. Vikkula; http://www.icp.be/vikkula)
• the rational design of anti-trypanosome drugs (F. Opperdoes, P. Michels;http://www.icp.be/trop)
• oxidative protein folding (J.-F. Collet; http://www.icp.be/grm)
Services offered
Diagnosis of hereditary diseases
Specialised equipments
• Instant imager
• Automatic DNA sequencing
• Microarrays (Affymetrix)
• HPLC
• dHPLC
Keywords
metabolism, glycolysis, cancer, trypanosoma, inborn errors
International contributions
1.T. Sluysmans, UCL, Cliniques St Luc, Service de Cardiologie pédiatrique, Bruxelles, Belgium
2. R. Vanwijck, B. Bayet, UCL, Cliniques St Luc, Chirurgie expérimentale, Bruxelles, Belgium
3. A. Ferrant, UCL, Cliniques St Luc, Unité d'Hématologie, Bruxelles, Belgium
4. J. Jaeken, G. Matthijs, Dr. K. Devriendt, KULeuven, U.Z. Gasthuisberg, Belgium
5. J. Meessens, VUB, Vlaams Interuniversitair Instituut voor Biotechnologie, Lab. voor Ultrastructuur, Brussels, Belgium
6. A. Burny, Faculté des Sciences Agronomiques à Gembloux, Belgium
7. B. Bakker, Free University. Amsterdam, Amsterdam, The Netherlands
8. L. Gilmore, University of Edinburgh, United Kingdom
9. C. Blonski, Université. Paul Sabatier, Toulouse, France.
10. O. Enjolras, Hôpital d’Enfants Armand Trousseau, Paris, France
11. A. Dompmartin, Centre Hospitalier Universitaire, Dermatologie, Caen, France
12. Ph. Pellerin, CHRU Lille, Hôpital Roger Salingro, Chirurgie plastique, reconstructrice & esthétique, Lille, France
13. M. Vaghi, Azienda Ospedaliera G. Salvini, Vascular Surgery, Milan, Italy
14. S. Ivarsson, Malmö University Hospital, Dept Pediatrics, Malmö, Sweden
15. C. Clayton, Univeristät. Heidelberg, Heidelberg, Germany
16. Ch. Meier, Hamburg University, Institute of Organic Chemistry, Hamburg, Germany
17. H. Santos, Instituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa, Lisbon, Portugal
18. F. Scaravilli, Institute of Neurology, Dept Neuropathology, London, United Kingdom
19. W. Hol, University of Washington, Dept. of Biological Structure, Seattle, USA.
20. B.R. Olsen. Harvard Medical School, Dept of Cell Biology, Boston, USA
21. J.B. Mulliken, Children's Hospital and Harvard Medical School, Division of Plastic Surgery, Boston, USA
22. E. Thonnard, Rush Presbyterian St Luke's Medical Center, Biochemistry, Chicago, Illinois, USA
23. D. Wirz, Chemical Engineering Department, University of Baltimore, USA
24. J.C.A. Bardwell, U. Jakob, Uiversity of Michigan, Dept of Molecular and Devlopmental Biology, Ann Arbor, USA
25. A. Uttaro, University of Rosario, Instituto de Biologia molecuar y celular, Santa Fe, Argentina
26. M. Abramowiccz, Hôpital Erasme, Centre de Génétique, Université Libre de Bruxelles, Belgium
27. J. Bischoff, The Children's Hospital, Harvard Medical School, Boston, USA
28. K. Alitalo, Biomedicum, University of Helsinki, Helsinki, Finland
29. S. Yla-Herttuala, University of Kuopio, Kuopio, Finland
30. L. Cresson-Welsh, University of Uppsala, Uppsala, Sweden
31. H. Augustin, Tumor Biology Center, Freiburg, Germany
32. I. Frieden, University of California San Francisco, Medical School, Dept Pediatrics, San Francisco, USA
33 A. Pennington, St. Vincent’s Hospital, Dept. of Surgery, Fitzroy, Australia
34. S. Watanabe, Tokyo Rosai Hospital, Div. of Plastic Surgery, Tokyo, Japan
35. N. Ruiz, Universit of Princeton, Department of Molecular Genetics, Princeton, New Jersey, USA
36. T. Baltz, F. Bringaud, University of Bordeaux, Laboratoire de Génomique fonctionnelle des Trypanosomatidés, Bordeaux, France
37. J. Dubois, Hôpital Sainte Justine, Montreal, Canada
38. I. Frieden, University of California San Francisco, San Francisco, USA
39. K. Devriendt, Center for Human Genetics, KUL, Leuven, Belgium
40. V. Sybert, University of Washington School of Medicine, Seattle, USA
41. M.R. Cordisco, Hospital Nacional de Pediatria "Prof. Dr. Juan P. Garrahan", Buenos Aires, Argentina
42. S. Fishman, Children’s Hospital, Harvard Medical School, Boston, USA
43. L. Kangesu, St Andrews Centre for Plastic Surgery, Broomfield Hospital, Chelmford, UK
44. P. Rieu, Universitair Medisch Centrum/Cluster Hoofd-Hals-Huid/UMC St Radboud, Nijmegen, The Netherlands
45. N. Van Regemorter, Hôpital Erasme, Centre de Génétique, Université Libre de Bruxelles, Belgium
Patents et licences
Patent(s) : no Licences : no
Staff of the research unit (in full time equivalent)
Number of researchers : 52 - Number of technical and administrative staff : 16
Training activities
Training : no
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